Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer

Pemetrexed (PEM) improves the overall survival of patients with advanced non-small cell lung cancer (NSCLC) when administered as maintenance therapy. However, PEM resistance often appears during the therapy. Although thymidylate synthase is known to be responsible for PEM resistance, no other mechan...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Tanino, Ryosuke, Tsubata, Yukari, Harashima, Nanae, Harada, Mamoru, Isobe, Takeshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2018
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908287/
https://ncbi.nlm.nih.gov/pubmed/29682186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24704
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