RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia

Leukemic cells often carry chromosome aberrations which generate chimeric genes of pathogenetic, diagnostic, and prognostic importance. New rearrangements giving rise to novel fusion genes define hitherto unrecognized genetic leukemia subgroups. G-banding, fluorescence in situ hybridization (FISH),...

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Опубликовано в: :PLoS One
Главные авторы: Panagopoulos, Ioannis, Gorunova, Ludmila, Jacobsen, Eva-Marie, Andersen, Kristin, Micci, Francesca, Heim, Sverre
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908135/
https://ncbi.nlm.nih.gov/pubmed/29672642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196181
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