RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report

Fluorescence in situ hybridization examination of a pediatric AML patient whose bone marrow cells carried trisomy 4 and FLT3-ITD mutation, demonstrated that part of the RUNX1 probe had unexpectedly moved to chromosome band 6q25 indicating a cryptic t(6;21)(q25;q22) translocation. RNA sequencing show...

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Publicat a:Oncol Rep
Autors principals: Panagopoulos, Ioannis, Torkildsen, Synne, Gorunova, Ludmila, Ulvmoen, Aina, Tierens, Anne, Zeller, Bernward, Heim, Sverre
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055202/
https://ncbi.nlm.nih.gov/pubmed/27667292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.5119
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