Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)

RNA-sequencing of a case of acute myeloid leukemia with the bone marrow karyotype 46,XY,t(2;14)(q22;q32)[5]/47,XY,idem,+?4,del(6)(q13q21)[cp6]/46,XY[4] showed that the t(2;14) generated a ZEB2-BCL11B chimera in which exon 2 of ZEB2 (nucleotide 595 in the sequence with accession number NM_014795.3) w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Torkildsen, Synne, Gorunova, Ludmila, Beiske, Klaus, Tjønnfjord, Geir E., Heim, Sverre, Panagopoulos, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505893/
https://ncbi.nlm.nih.gov/pubmed/26186352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132736
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