Down‐regulation of PKM2 enhances anticancer efficiency of THP on bladder cancer

Pyruvate kinase M2 (PKM2) regulates the final step of glycolysis levels that are correlated with the sensitivity of anticancer chemotherapeutic drugs. THP is one of the major drugs used in non‐muscle‐invasive bladder cancer instillation chemotherapy. However, low response ratio of THP (19.7%) treatm...

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Publicat a:J Cell Mol Med
Autors principals: Su, Qiongli, Tao, Ting, Tang, Lei, Deng, Jun, Darko, Kwame Oteng, Zhou, Sichun, Peng, Mei, He, Shanping, Zeng, Qing, Chen, Alex F., Yang, Xiaoping
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908113/
https://ncbi.nlm.nih.gov/pubmed/29512924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13571
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