Down‐regulation of PKM2 enhances anticancer efficiency of THP on bladder cancer

Pyruvate kinase M2 (PKM2) regulates the final step of glycolysis levels that are correlated with the sensitivity of anticancer chemotherapeutic drugs. THP is one of the major drugs used in non‐muscle‐invasive bladder cancer instillation chemotherapy. However, low response ratio of THP (19.7%) treatm...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Su, Qiongli, Tao, Ting, Tang, Lei, Deng, Jun, Darko, Kwame Oteng, Zhou, Sichun, Peng, Mei, He, Shanping, Zeng, Qing, Chen, Alex F., Yang, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908113/
https://ncbi.nlm.nih.gov/pubmed/29512924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13571
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