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Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis

In Drosophila, the JNK pathway eliminates by apoptosis aberrant cells that appear in development. It also performs other functions associated with cell proliferation, but analysis of the latter is hindered by the pro-apoptotic activity. We report the response of apoptosis-deficient cells to transien...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pinal, Noelia, Martín, María, Medina, Izarne, Morata, Ginés
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906466/
https://ncbi.nlm.nih.gov/pubmed/29670104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04000-6
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