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Bone Marrow Transplant Induced Alterations in Notch Signaling Promote Pathologic Th17 Responses to γ-Herpesvirus Infection

Idiopathic pneumonia syndrome (IPS) is a common, often fatal, complication following hematopoietic stem cell transplantation (HSCT) characterized by severe pneumonitis and interstitial fibrosis. Fully reconstituted syngeneic bone marrow transplant (BMT) mice infected with murine gammaherpesvirus (γH...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Gurczynski, Stephen J., Zhou, Xiaofeng, Flaherty, Melanie, Wilke, Carol A., Moore, Bethany B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906203/
https://ncbi.nlm.nih.gov/pubmed/29044226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2017.85
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