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Loss of CCR2 signaling alters leukocyte recruitment and exacerbates γ-herpesvirus-induced pneumonitis and fibrosis following bone marrow transplantation

CCR2-expressing leukocytes are required for the progression of fibrosis in models of induced lung injury as well as models of bone marrow transplant (BMT)-related idiopathic pneumonia syndrome. Infection with murid γ-herpesvirus-68 (γHV-68) results in severe pneumonitis and pulmonary fibrosis follow...

詳細記述

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書誌詳細
出版年:Am J Physiol Lung Cell Mol Physiol
主要な著者: Gurczynski, Stephen J., Procario, Megan C., O'Dwyer, David N., Wilke, Carol A., Moore, Bethany B.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142213/
https://ncbi.nlm.nih.gov/pubmed/27448666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00193.2016
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