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The mitochondrial GSH systems in CA1 pyramidal cells and astrocytes react differently during oxygen-glucose deprivation and reperfusion

Pyramidal cells and astrocytes have differential susceptibility to oxygen-glucose deprivation and reperfusion (OGD-RP). It is known that excessive reactive oxygen species (ROS) in mitochondria initiates the cell death, while glutathione (GSH) is one of the major defenses against ROS. Although it is...

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Bibliographic Details
Published in:ACS Chem Neurosci
Main Authors: Yin, Bocheng, Barrionuevo, Germán, Weber, Stephen G.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906174/
https://ncbi.nlm.nih.gov/pubmed/29172440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00369
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