Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers

BACKGROUND: Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP) of V. cholerae are involved in mediating protecti...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Islam, Kamrul, Hossain, Motaher, Kelly, Meagan, Mayo Smith, Leslie M., Charles, Richelle C., Bhuiyan, Taufiqur Rahman, Kováč, Pavol, Xu, Peng, LaRocque, Regina C., Calderwood, Stephen B., Simon, Jakub K., Chen, Wilbur H., Haney, Douglas, Lock, Michael, Lyon, Caroline E., Kirkpatrick, Beth D., Cohen, Mitchell, Levine, Myron M., Gurwith, Marc, Harris, Jason B., Qadri, Firdausi, Ryan, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906022/
https://ncbi.nlm.nih.gov/pubmed/29624592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006376
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