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Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss

Reactive oxygen species exert important functions in regulating several cellular signalling pathways. However, an excessive accumulation of reactive oxygen species can perturb the redox homeostasis leading to oxidative stress, a condition which has been associated to many neurodegenerative disorders...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Biosa, Alice, Sanchez-Martinez, Alvaro, Filograna, Roberta, Terriente-Felix, Ana, Alam, Sarah M, Beltramini, Mariano, Bubacco, Luigi, Bisaglia, Marco, Whitworth, Alexander J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905640/
https://ncbi.nlm.nih.gov/pubmed/29529199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy069
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