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Seipin deficiency leads to increased endoplasmic reticulum stress and apoptosis in mammary gland alveolar epithelial cells during lactation()
Seipin is an integral endoplasmic reticulum (ER) membrane protein encoded by Berardinelli–Seip congenital lipodystrophy type 2 (BSCL2/Bscl2) gene. Most litters (59%) from Bscl2(−/−) dams mated with wild type (WT) (Bscl2(+/+)) males did not survive postnatal day 5 (PND5) and pups (Bscl2(+/−)) lacked...
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| Publicado no: | Biol Reprod |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5905587/ https://ncbi.nlm.nih.gov/pubmed/29236949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/iox169 |
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