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Expression of pyruvate kinase M2 in human bladder cancer and its correlation with clinical parameters and prognosis

BACKGROUND: Pyruvate kinase M2 (PKM2) is a key regulator of the Warburg effect and has critical functions in glycolysis, contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis, and apoptosis. The high expression of PKM2 in various solid tumors renders it a potentia...

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Enregistré dans:
Détails bibliographiques
Publié dans:Onco Targets Ther
Auteurs principaux: Huang, Changkun, Huang, Zhichao, Bai, Peiming, Luo, Guangcheng, Zhao, Xiaokun, Wang, Xinjun
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905464/
https://ncbi.nlm.nih.gov/pubmed/29695915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S152999
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