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Expression of pyruvate kinase M2 in human bladder cancer and its correlation with clinical parameters and prognosis

BACKGROUND: Pyruvate kinase M2 (PKM2) is a key regulator of the Warburg effect and has critical functions in glycolysis, contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis, and apoptosis. The high expression of PKM2 in various solid tumors renders it a potentia...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Huang, Changkun, Huang, Zhichao, Bai, Peiming, Luo, Guangcheng, Zhao, Xiaokun, Wang, Xinjun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905464/
https://ncbi.nlm.nih.gov/pubmed/29695915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S152999
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