Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1

Merkel cell polyomavirus (MCV) plays a causal role in ∼80% of Merkel cell carcinomas (MCC). MCV is clonally integrated into the MCC tumor genome, which results in persistent expression of large T (LT) and small T (sT) antigen oncoproteins encoded by the early locus. In MCV-positive MCC tumors, LT is...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Velásquez, Celestino, Amako, Yutaka, Harold, Alexis, Toptan, Tuna, Chang, Yuan, Shuda, Masahiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905237/
https://ncbi.nlm.nih.gov/pubmed/29696010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00713
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