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A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders

BACKGROUND: Mutations in the SHANK genes, which encode postsynaptic scaffolding proteins, have been linked to a spectrum of neurodevelopmental disorders. The SHANK genes and the schizophrenia-associated microRNA-137 show convergence on several levels, as they are both expressed at the synapse, influ...

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Detalhes bibliográficos
Publicado no:J Neurodev Disord
Main Authors: de Sena Cortabitarte, Ana, Berkel, Simone, Cristian, Flavia-Bianca, Fischer, Christine, Rappold, Gudrun A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905159/
https://ncbi.nlm.nih.gov/pubmed/29665782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11689-018-9233-1
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