Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

BACKGROUND: Periprostatic adipose tissue (PPAT) has been recognized to associate with prostate cancer (PCa) aggressiveness and progression. Here, we sought to investigate whether excess adiposity modulates the methylome of PPAT in PCa patients. DNA methylation profiling was performed in PPAT from ob...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Cheng, Yan, Monteiro, Cátia, Matos, Andreia, You, Jiaying, Fraga, Avelino, Pereira, Carina, Catalán, Victoria, Rodríguez, Amaia, Gómez-Ambrosi, Javier, Frühbeck, Gema, Ribeiro, Ricardo, Hu, Pingzhao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904983/
https://ncbi.nlm.nih.gov/pubmed/29692867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0490-3
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