Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

BACKGROUND: Periprostatic adipose tissue (PPAT) has been recognized to associate with prostate cancer (PCa) aggressiveness and progression. Here, we sought to investigate whether excess adiposity modulates the methylome of PPAT in PCa patients. DNA methylation profiling was performed in PPAT from ob...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Cheng, Yan, Monteiro, Cátia, Matos, Andreia, You, Jiaying, Fraga, Avelino, Pereira, Carina, Catalán, Victoria, Rodríguez, Amaia, Gómez-Ambrosi, Javier, Frühbeck, Gema, Ribeiro, Ricardo, Hu, Pingzhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904983/
https://ncbi.nlm.nih.gov/pubmed/29692867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0490-3
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