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Detection of mitomycin C‐induced testicular toxicity by micronucleus assay in mice

Background, Aims and Methods:  Mitomycin C is a promising cancer agent that has been shown to inhibit DNA synthesis. Our previous study showed that mitomycin C induces spermatogenic cell apoptosis in the mouse testis. By using TdT‐mediated dUTP‐biotin nick‐end labeling in the study, we confirmed tha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Reprod Med Biol
Hauptverfasser: Nakagawa, Soichi, Mori, Chisato
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd. 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904686/
https://ncbi.nlm.nih.gov/pubmed/29699167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1445-5781.2003.00023.x
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