Effects of Bioreductive Agents, Tirapazamine and Mitomycin C, on Quiescent Cell Populations in Solid Tumors, Evaluated by Micronucleus Assay

Mice bearing transplantable solid tumors received 10 intraperitoneal administrations of 5‐bromo‐2′‐deoxyuridine (BrdU) to label the proliferating (P) tumor cells, and were then irradiated with (60)Cogamma‐rays or injected with cis‐diamminedichloroplatinum (II) (cisplatin). The tumor cells were isola...

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Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Masunaga, Shin‐ichiro, Ono, Koji, Hori, Hitoshi, Shibata, Toru, Suzuki, Minoru, Kinashi, Yuko, Takagaki, Masao, Akaboshi, Mitsuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 1997
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921522/
https://ncbi.nlm.nih.gov/pubmed/9369940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00468.x
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