Can oliceridine (TRV130), an ideal novel µ receptor G protein pathway selective (µ-GPS) modulator, provide analgesia without opioid-related adverse reactions?

All drugs have both favorable therapeutic and untoward adverse effects. Conventional opioid analgesics possess both analgesia and adverse reactions, such as nausea, vomiting, and respiratory depression. The opioid ligand binds to µ opioid receptor and non-selectively activates two intracellular sign...

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Detalhes bibliográficos
Publicado no:Korean J Pain
Main Authors: Ok, Hwoe Gyeong, Kim, Su Young, Lee, Su Jung, Kim, Tae Kyun, Huh, Billy K, Kim, Kyung Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Pain Society 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904350/
https://ncbi.nlm.nih.gov/pubmed/29686804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3344/kjp.2018.31.2.73
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