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Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records

Bipolar disorder (BD) is a heritable mood disorder characterized by episodes of mania and depression. Although genomewide association studies (GWAS) have successfully identified genetic loci contributing to BD risk, sample size has become a rate-limiting obstacle to genetic discovery. Electronic hea...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Chen, Chia-Yen, Lee, Phil H., Castro, Victor M., Minnier, Jessica, Charney, Alexander W., Stahl, Eli A., Ruderfer, Douglas M., Murphy, Shawn N., Gainer, Vivian, Cai, Tianxi, Jones, Ian, Pato, Carlos N., Pato, Michele T., Landén, Mikael, Sklar, Pamela, Perlis, Roy H., Smoller, Jordan W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904248/
https://ncbi.nlm.nih.gov/pubmed/29666432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0133-7
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