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Exposure to Phthalate, an Endocrine Disrupting Chemical, Alters the First Trimester Placental Methylome and Transcriptome in Women

Phthalates are known endocrine disruptors and associated with decreased fecundity, pregnancy loss, and adverse obstetrical outcomes, however the underlying mechanisms remain to be established. Environmental factors can influence gene expression and cell function by modifying epigenetic marks, impact...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Grindler, N. M., Vanderlinden, L., Karthikraj, R., Kannan, K., Teal, S., Polotsky, A. J., Powell, T. L., Yang, I. V., Jansson, T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904105/
https://ncbi.nlm.nih.gov/pubmed/29666409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24505-w
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