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Exposure to Phthalate, an Endocrine Disrupting Chemical, Alters the First Trimester Placental Methylome and Transcriptome in Women

Phthalates are known endocrine disruptors and associated with decreased fecundity, pregnancy loss, and adverse obstetrical outcomes, however the underlying mechanisms remain to be established. Environmental factors can influence gene expression and cell function by modifying epigenetic marks, impact...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Grindler, N. M., Vanderlinden, L., Karthikraj, R., Kannan, K., Teal, S., Polotsky, A. J., Powell, T. L., Yang, I. V., Jansson, T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904105/
https://ncbi.nlm.nih.gov/pubmed/29666409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24505-w
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