Association of Decreased Percentage of Vδ2(+)Vγ9(+) γδ T Cells With Disease Severity in Multiple Sclerosis

We recently reported that deletion-type copy number variations of the T cell receptor (TCR) γ, α, and δ genes greatly enhanced susceptibility to multiple sclerosis (MS). However, the effect of abnormal TCR γδ gene rearrangement on MS pathogenesis remains unknown. In the present study, we aimed to cl...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Maimaitijiang, Guzailiayi, Shinoda, Koji, Nakamura, Yuri, Masaki, Katsuhisa, Matsushita, Takuya, Isobe, Noriko, Yamasaki, Ryo, Yoshikai, Yasunobu, Kira, Jun-ichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903009/
https://ncbi.nlm.nih.gov/pubmed/29692781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00748
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