Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa

BACKGROUND: Retinitis pigmentosa (RP) is a group of hereditary retinal neurodegenerative conditions characterized by primary dysfunction and death of photoreceptor cells, resulting in visual loss and, eventually, blindness. To date, no effective therapies have been transferred to clinic. Given the d...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Sánchez-Cruz, Alonso, Villarejo-Zori, Beatriz, Marchena, Miguel, Zaldivar-Díez, Josefa, Palomo, Valle, Gil, Carmen, Lizasoain, Ignacio, de la Villa, Pedro, Martínez, Ana, de la Rosa, Enrique J., Hernández-Sánchez, Catalina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902946/
https://ncbi.nlm.nih.gov/pubmed/29661219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0251-y
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