A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples

BACKGROUND: Colorectal cancer is the fourth cause of cancer-related deaths worldwide, though detection at early stages associates with good prognosis. Thus, there is a clear demand for novel non-invasive tests for the early detection of colorectal cancer and premalignant advanced adenomas, to be use...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Gallardo-Gómez, María, Moran, Sebastian, Páez de la Cadena, María, Martínez-Zorzano, Vicenta Soledad, Rodríguez-Berrocal, Francisco Javier, Rodríguez-Girondo, Mar, Esteller, Manel, Cubiella, Joaquín, Bujanda, Luis, Castells, Antoni, Balaguer, Francesc, Jover, Rodrigo, De Chiara, Loretta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902929/
https://ncbi.nlm.nih.gov/pubmed/29686738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0487-y
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