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Pridopidine Reverses Phencyclidine-Induced Memory Impairment
Pridopidine is in clinical trials for Huntington's disease treatment. Originally developed as a dopamine D(2) receptor (D(2)R) ligand, pridopidine displays about 100-fold higher affinity for the sigma-1 receptor (sigma-1R). Interestingly, pridopidine slows disease progression and improves motor...
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| Foilsithe in: | Front Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Frontiers Media S.A.
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5902730/ https://ncbi.nlm.nih.gov/pubmed/29692729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00338 |
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