Structural studies on radiopharmaceutical DOTA-minigastrin analogue (CP04) complexes and their interaction with CCK2 receptor

BACKGROUND: The cholecystokinin receptor subtype 2 (CCK-2R) is an important target for diagnostic imaging and targeted radionuclide therapy (TRNT) due to its overexpression in certain cancers (e.g., medullary thyroid carcinoma (MTC)), thus matching with a theranostic principle. Several peptide conju...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Lipiński, Piotr F. J., Garnuszek, Piotr, Maurin, Michał, Stoll, Raphael, Metzler-Nolte, Nils, Wodyński, Artur, Dobrowolski, Jan Cz., Dudek, Marta K., Orzełowska, Monika, Mikołajczak, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902437/
https://ncbi.nlm.nih.gov/pubmed/29663167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0387-3
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