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Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia

Biliary atresia is a progressive infantile cholangiopathy of complex pathogenesis. Although early diagnosis and surgery are the best predictors of treatment response, current diagnostic approaches are imprecise and time consuming. We used large-scale, quantitative serum proteomics at the time of dia...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Lertudomphonwanit, Chatmanee, Mourya, Reena, Fei, Lin, Zhang, Yue, Gutta, Sridevi, Yang, Li, Bove, Kevin E., Shivakumar, Pranavkumar, Bezerra, Jorge A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902315/
https://ncbi.nlm.nih.gov/pubmed/29167395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan8462
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