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Characterization of the Functional Variance in MbtH-like Protein Interactions with a Nonribosomal Peptide Synthetase

Many nonribosomal peptide synthetases (NRPSs) require MbtH-like proteins (MLPs) for solubility or for activation of amino acid substrate by the adenylation domain. MLPs are capable of functional crosstalk with noncognate NRPSs at varying levels. Using enterobactin biosynthesis in Escherichia coli as...

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Publicado en:Biochemistry
Main Authors: Schomer, Rebecca A., Thomas, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902190/
https://ncbi.nlm.nih.gov/pubmed/28880538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00517
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