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Interactions between genetic variation and cellular environment in skeletal muscle gene expression

From whole organisms to individual cells, responses to environmental conditions are influenced by genetic makeup, where the effect of genetic variation on a trait depends on the environmental context. RNA-sequencing quantifies gene expression as a molecular trait, and is capable of capturing both ge...

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Veröffentlicht in:PLoS One
Hauptverfasser: Taylor, D. Leland, Knowles, David A., Scott, Laura J., Ramirez, Andrea H., Casale, Francesco Paolo, Wolford, Brooke N., Guan, Li, Varshney, Arushi, Albanus, Ricardo D’Oliveira, Parker, Stephen C. J., Narisu, Narisu, Chines, Peter S., Erdos, Michael R., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Stegle, Oliver, Boehnke, Michael, Birney, Ewan, Collins, Francis S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901994/
https://ncbi.nlm.nih.gov/pubmed/29659628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195788
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