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Photoactivated inhibition of cathepsin K in a 3D tumor model

Collagenolytic activity of cathepsin K is important for many physiological and pathological processes including osteoclast-mediated bone degradation, macrophage function and fibroblast-mediated matrix remodeling. Here, we report application of a light-activated inhibitor for controlling activity of...

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Detalhes bibliográficos
Publicado no:Biol Chem
Main Authors: Herroon, Mackenzie K., Sharma, Rajgopal, Rajagurubandara, Erandi, Turro, Claudia, Kodanko, Jeremy J., Podgorski, Izabela
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901740/
https://ncbi.nlm.nih.gov/pubmed/26901495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2015-0274
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