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Heart and Nervous System Pathology in Compound Heterozygous Friedreich Ataxia

In a small percentage of patients with Friedreich ataxia (FA), the pathogenic mutation is compound heterozygous, consisting of a guanine–adenine–adenine (GAA) trinucleotide repeat expansion in one allele, and a deletion, point mutation, or insertion in the other. In 2 cases of compound heterozygous...

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Dades bibliogràfiques
Publicat a:J Neuropathol Exp Neurol
Autors principals: Becker, Alyssa B., Qian, Jiang, Gelman, Benjamin B., Yang, Michele, Bauer, Peter, Koeppen, Arnulf H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901083/
https://ncbi.nlm.nih.gov/pubmed/28789479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlx047
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