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Genetic ablation of carbonic anhydrase IX disrupts gastric barrier function via claudin‐18 downregulation and acid backflux
AIM: This study aimed to explore the molecular mechanisms for the parietal cell loss and fundic hyperplasia observed in gastric mucosa of mice lacking the carbonic anhydrase 9 (CAIX). METHODS: We assessed the ability of CAIX‐knockout and WT gastric surface epithelial cells to withstand a luminal aci...
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| Publicado no: | Acta Physiol (Oxf) |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5901031/ https://ncbi.nlm.nih.gov/pubmed/28748627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12923 |
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