The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

Enzymes at the phosphoenolpyruvate (PEP)–pyruvate–oxaloacetate or anaplerotic (ANA) node control the metabolic flux to glycolysis, gluconeogenesis, and anaplerosis. Here we used genetic, biochemical, and (13)C isotopomer analysis to characterize the role of the enzymes at the ANA node in intracellul...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Basu, Piyali, Sandhu, Noor, Bhatt, Apoorva, Singh, Albel, Balhana, Ricardo, Gobe, Irene, Crowhurst, Nicola A., Mendum, Tom A., Gao, Liang, Ward, Jane L., Beale, Michael H., McFadden, Johnjoe, Beste, Dany J. V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900758/
https://ncbi.nlm.nih.gov/pubmed/29475946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001839
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