The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

Enzymes at the phosphoenolpyruvate (PEP)–pyruvate–oxaloacetate or anaplerotic (ANA) node control the metabolic flux to glycolysis, gluconeogenesis, and anaplerosis. Here we used genetic, biochemical, and (13)C isotopomer analysis to characterize the role of the enzymes at the ANA node in intracellul...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Basu, Piyali, Sandhu, Noor, Bhatt, Apoorva, Singh, Albel, Balhana, Ricardo, Gobe, Irene, Crowhurst, Nicola A., Mendum, Tom A., Gao, Liang, Ward, Jane L., Beale, Michael H., McFadden, Johnjoe, Beste, Dany J. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900758/
https://ncbi.nlm.nih.gov/pubmed/29475946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001839
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