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Combined Acylselenourea–Diselenide Structures: New Potent and Selective Antitumoral Agents as Autophagy Activators

[Image: see text] A series of 16 new diselenide–acylselenourea conjugates have been designed following the fragment-based drug strategy. Compound in vitro cytotoxic potential was evaluated against six human cancer cell lines and two nonmalignant derived cell lines with the aim of determining their p...

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Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Garnica, Pablo, Encío, Ignacio, Plano, Daniel, Palop, Juan A., Sanmartín, Carmen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2018
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900345/
https://ncbi.nlm.nih.gov/pubmed/29670691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00482
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