Synthesis and Pharmacological Screening of Several Aroyl and Heteroaroyl Selenylacetic Acid Derivatives as Cytotoxic and Antiproliferative Agents

The synthesis and cytotoxic activity of a series of twenty six aroyl and heteroaroyl selenylacetic acid derivatives of general formula Ar-CO-Se-CH(2)-COOH or Heterar-CO-Se-CH(2)-COOH are reported. The synthesis was carried out by reaction of acyl chlorides with sodium hydrogen selenide, prepared in...

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Veröffentlicht in:Molecules
Hauptverfasser: Sanmartín, Carmen, Plano, Daniel, Domínguez, Enrique, Font, María, Calvo, Alfonso, Prior, Celia, Encío, Ignacio, Palop, Juan Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254723/
https://ncbi.nlm.nih.gov/pubmed/19783927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14093313
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