A carregar...
Exploring the structural origins of cryptic sites on proteins
Molecular dynamics (MD) simulations of proteins reveal the existence of many transient surface pockets; however, the factors determining what small subset of these represent druggable or functionally relevant ligand binding sites, called “cryptic sites,” are not understood. Here, we examine multiple...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899430/ https://ncbi.nlm.nih.gov/pubmed/29581267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711490115 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|