Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats

Signaling via the colony-stimulating factor 1 receptor (CSF1R) controls the survival, differentiation, and proliferation of macrophages. Mutations in CSF1 or CSF1R in mice and rats have pleiotropic effects on postnatal somatic growth. We tested the possible application of pig CSF1-Fc fusion protein...

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Bibliografske podrobnosti
izdano v:Am J Physiol Gastrointest Liver Physiol
Main Authors: Pridans, Clare, Sauter, Kristin A., Irvine, Katharine M., Davis, Gemma M., Lefevre, Lucas, Raper, Anna, Rojo, Rocio, Nirmal, Ajit J., Beard, Philippa, Cheeseman, Michael, Hume, David A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899243/
https://ncbi.nlm.nih.gov/pubmed/29351395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00343.2017
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