Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats

Signaling via the colony-stimulating factor 1 receptor (CSF1R) controls the survival, differentiation, and proliferation of macrophages. Mutations in CSF1 or CSF1R in mice and rats have pleiotropic effects on postnatal somatic growth. We tested the possible application of pig CSF1-Fc fusion protein...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Pridans, Clare, Sauter, Kristin A., Irvine, Katharine M., Davis, Gemma M., Lefevre, Lucas, Raper, Anna, Rojo, Rocio, Nirmal, Ajit J., Beard, Philippa, Cheeseman, Michael, Hume, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899243/
https://ncbi.nlm.nih.gov/pubmed/29351395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00343.2017
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