Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina

Mutations in the Norrin (NDP) gene cause severe developmental blood vessel defects in the retina leading to congenital blindness. In the retina of Ndph-knockout mice only the superficial capillary network develops. Here, a detailed characterization of this mouse model at late stages of the disease u...

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Udgivet i:Sci Rep
Main Authors: Beck, Susanne C., Karlstetter, Marcus, Garcia Garrido, Marina, Feng, Yuxi, Dannhausen, Katharina, Mühlfriedel, Regine, Sothilingam, Vithiyanjali, Seebauer, Britta, Berger, Wolfgang, Hammes, Hans-Peter, Seeliger, Mathias W., Langmann, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899099/
https://ncbi.nlm.nih.gov/pubmed/29654250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24476-y
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