Myotubularin related protein-2 and its phospholipid substrate PIP(2) control Piezo2-mediated mechanotransduction in peripheral sensory neurons

Piezo2 ion channels are critical determinants of the sense of light touch in vertebrates. Yet, their regulation is only incompletely understood. We recently identified myotubularin related protein-2 (Mtmr2), a phosphoinositide (PI) phosphatase, in the native Piezo2 interactome of murine dorsal root...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Narayanan, Pratibha, Hütte, Meike, Kudryasheva, Galina, Taberner, Francisco J, Lechner, Stefan G, Rehfeldt, Florian, Gomez-Varela, David, Schmidt, Manuela
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898911/
https://ncbi.nlm.nih.gov/pubmed/29521261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32346
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