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Cell-type specific splicing of Piezo2 regulates mechanotransduction
Piezo2 is a mechanically activated ion-channel required for touch discrimination, vibration detection and proprioception. Here we discovered that Piezo2 is extensively spliced, producing different Piezo2 isoforms with distinct properties. Sensory neurons from both mice and humans express a large rep...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741189/ https://ncbi.nlm.nih.gov/pubmed/29212024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.035 |
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