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Impaired Na(+)−K(+)-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury
Hyperuricemia contributes to renal inflammation. We aimed to investigate the role of Na(+)–K(+)–ATPase (NKA) in hyperuricemia-induced renal tubular injury. Human primary proximal tubular epithelial cells (PTECs) were incubated with uric acid (UA) at increasing doses or for increasing lengths of time...
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| 出版年: | Exp Mol Med |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5898891/ https://ncbi.nlm.nih.gov/pubmed/29497172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.287 |
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