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AMPK alleviates high uric acid-induced Na(+)-K(+)-ATPase signaling impairment and cell injury in renal tubules
One of the mechanisms in hyperuricemia (HUA)-induced renal tubular injury is the impairment of Na(+)-K(+)-ATPase (NKA) signaling, which further triggers inflammation, autophagy, and mitochondrial dysfunction and leads to cell injury. Here, we used RNA sequencing to screen the most likely regulators...
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| Publicado no: | Exp Mol Med |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6531502/ https://ncbi.nlm.nih.gov/pubmed/31118410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0254-y |
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