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Engineering Multifunctional RNAi Nanomedicine to Concurrently Target Cancer Hallmarks for Combinatorial Therapy

Cancer hallmarks allow the complexity and heterogeneity of tumor biology to be better understood, leading to the discovery of various promising targets for cancer therapy. An amorphous iron oxide nanoparticle (NP)-based RNAi strategy is developed to co-target two cancer hallmarks. The NP technology...

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Dettagli Bibliografici
Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Liu, Yanlan, Ji, Xiaoyuan, Tong, Winnie W. L., Askhatova, Diana, Yang, Tingyuan, Cheng, Hongwei, Wang, Yuzhuo, Shi, Jinjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898800/
https://ncbi.nlm.nih.gov/pubmed/29276823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710144
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