Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation

There is evidence that dendritic cells (DCs) undergo age-related changes that modulate their function with their key role being priming antigen-specific effector T cells. This occurs once DCs develop into antigen-presenting cells in response to stimuli/danger signals. However, the effects of aging o...

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Veröffentlicht in:PLoS One
Hauptverfasser: Gardner, Joanne K., Cornwall, Scott M. J., Musk, Arthur W., Alvarez, John, Mamotte, Cyril D. S., Jackaman, Connie, Nowak, Anna K., Nelson, Delia J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898732/
https://ncbi.nlm.nih.gov/pubmed/29652910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195313
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